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MedSurg PI, LLC

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Published in Cureus: The Essential Role of Medical Monitors in Clinical Trials

October 2, 2025 Susan Van Vactor

New in Cureus: we outline how independent Medical Monitors safeguard patient safety, ensure regulatory alignment, and deliver unbiased, real-time oversight from protocol design through signal detection. Drawing on practical duties, escalation pathways, and cautionary case examples (e.g., first-in-human and CAR-T), we argue that medical monitoring is a strategic necessity—not just a compliance checkbox.

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